South African Malaria Initiative

Working together to combat malaria.

"...information at the molecular level is vital to gain insights
into the pathogenesis of malaria, and potentially offers
the opportunity to develop better drugs."

~ Subra Suresh


The South African Malaria Initiative (SAMI) is a partnership established to facilitate the integration of malaria research and related capacity development in South Africa and the rest of Africa. The aim is to stimulate the use of modern molecular research tools to improve malaria prevention and control.


SAMI Mission:

The South African Malaria Initiative will facilitate an integrated programme of malaria research and capacity development in South Africa and eventually in the rest of Africa to improve malaria prevention and control. Modern research tools will be applied to malaria research. Outputs will include the identification and validation of drug and insecticidal targets, development of drug and insecticidal candidates, improved diagnostics, and new tools for gathering epidemiological information.


Benefits and purpose

  • Capacity building

  • Integration of social and epidemiological information with new intervention strategies

  • Creating links between researchers working on different topics in malaria

  • Raise funding

  • Focus on goals and deliverables

  • Brining advanced gene technologies to bear on all aspects of malaria research.

South Africa is in a unique position in possessing not only a strong technology base but also being positioned in a malaria endemic area with ready access to samples and information, and with the potential to carry out clinical trials locally. Moreover, scientists are well positioned to integrate research on the mosquito vector and the malaria parasite, for instance to track patterns of migration and related drug resistance.

SAMI aims to bring together key researchers in South Africa with a focus on molecular aspects of malaria drug and insecticide discovery, molecular epidemiology and diagnostics, to develop the critical mass required to generate real solutions to the malaria problem.

Local and international networks will be strengthened and partnerships developed to provide access to skills not currently available. At the same time, capacity building efforts will focus on growth of the local skills base, particularly in the use and application of new molecular and high throughput biological techniques.


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